Nanoparticle-enabled experimentally trained wavelet-domain denoising method for optical coherence tomography

Wavelet denoising of multiframe optical coherence tomography data

We introduce a novel speckle noise reduction algorithm for OCT images. Contrary to present approaches, the algorithm does not rely on simple averaging of multiple image frames or denoising on the final averaged image. Instead it uses wavelet decompositions of the single frames for a local noise and structure estimation. Based on this analysis, the wavelet detail coefficients are weighted, avera...

Wavelet domain compounding for speckle reduction in optical coherence tomography.

Visibility of optical coherence tomography (OCT) images can be severely degraded by speckle noise. A computationally efficient despeckling approach that strongly reduces the speckle noise is reported. It is based on discrete wavelet transform (DWT), but eliminates the conventional process of threshold estimation. By decomposing an image into different levels, a set of sub-band images are genera...

Sparsity based denoising of spectral domain optical coherence tomography images

In this paper, we make contact with the field of compressive sensing and present a development and generalization of tools and results for reconstructing irregularly sampled tomographic data. In particular, we focus on denoising Spectral-Domain Optical Coherence Tomography (SDOCT) volumetric data. We take advantage of customized scanning patterns, in which, a selected number of B-scans are imag...

NANOPARTICLE CONTRAST AGENTS FOR OPTICAL COHERENCE TOMOGRAPHY by

Time-gated Fourier-domain optical coherence tomography.

A novel optical coherence tomography (OCT) system is presented that combines Fourier-domain OCT with incoherent nonlinear time gating. By processing backscattered light in the optical domain, the user can select a restricted depth field of view for improved contrast and acquisition speed. This technique has the additional advantage that imaging is done in the infrared (approximately 1280 nm) bu...